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G-protein Gα(13) functions as a cytoskeletal and mitochondrial regulator to restrain osteoclast function

Excessive osteoclastic bone erosion disrupts normal bone remodeling and leads to bone loss in many skeletal diseases, including inflammatory arthritis, such as rheumatoid arthritis (RA) and psoriatic arthritis, periodontitis and peri-prosthetic loosening. Functional control of osteoclasts is critica...

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Detalles Bibliográficos
Autores principales: Nakano, Shinichi, Inoue, Kazuki, Xu, Cheng, Deng, Zhonghao, Syrovatkina, Viktoriya, Vitone, Gregory, Zhao, Liang, Huang, Xin-Yun, Zhao, Baohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414604/
https://www.ncbi.nlm.nih.gov/pubmed/30862896
http://dx.doi.org/10.1038/s41598-019-40974-z