Cargando…
G-protein Gα(13) functions as a cytoskeletal and mitochondrial regulator to restrain osteoclast function
Excessive osteoclastic bone erosion disrupts normal bone remodeling and leads to bone loss in many skeletal diseases, including inflammatory arthritis, such as rheumatoid arthritis (RA) and psoriatic arthritis, periodontitis and peri-prosthetic loosening. Functional control of osteoclasts is critica...
Autores principales: | Nakano, Shinichi, Inoue, Kazuki, Xu, Cheng, Deng, Zhonghao, Syrovatkina, Viktoriya, Vitone, Gregory, Zhao, Liang, Huang, Xin-Yun, Zhao, Baohong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414604/ https://www.ncbi.nlm.nih.gov/pubmed/30862896 http://dx.doi.org/10.1038/s41598-019-40974-z |
Ejemplares similares
-
Substrate stiffness regulates the differentiation profile and functions of osteoclasts via cytoskeletal arrangement
por: Wang, Qingxuan, et al.
Publicado: (2021) -
Loss of kinesin-14 results in aneuploidy via kinesin-5-dependent microtubule protrusions leading to chromosome cut
por: Syrovatkina, Viktoriya, et al.
Publicado: (2015) -
Downregulation of HBx Restrains Proliferation, Migration, and Invasion of HepG2 Cells
por: Huang, Chaoqun, et al.
Publicado: (2021) -
Osteoclasts are not a source of SLIT3
por: Li, Na, et al.
Publicado: (2020) -
Non-canonical Wnt signals regulate cytoskeletal remodeling in osteoclasts
por: Uehara, Shunsuke, et al.
Publicado: (2018)