Tissue resident and follicular Treg cell differentiation is regulated by CRAC channels

T regulatory (Treg) cells maintain immunological tolerance and organ homeostasis. Activated Treg cells differentiate into effector Treg subsets that acquire tissue-specific functions. Ca(2+) influx via Ca(2+) release-activated Ca(2+) (CRAC) channels formed by STIM and ORAI proteins is required for t...

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Detalles Bibliográficos
Autores principales: Vaeth, Martin, Wang, Yin-Hu, Eckstein, Miriam, Yang, Jun, Silverman, Gregg J., Lacruz, Rodrigo S., Kannan, Kasthuri, Feske, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414608/
https://www.ncbi.nlm.nih.gov/pubmed/30862784
http://dx.doi.org/10.1038/s41467-019-08959-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414608/
https://www.ncbi.nlm.nih.gov/pubmed/30862784
http://dx.doi.org/10.1038/s41467-019-08959-8

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