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Crotoxin promotes macrophage reprogramming towards an antiangiogenic phenotype

Crotoxin (CTX) is the primary toxin of South American rattlesnake Crotalus durissus terrificus venom. CTX reduces tumour mass, and tumour cell proliferation and these effects seem to involve the formation of new vessels. Angiogenesis has a key role in tumour growth and progression and is regulated b...

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Detalles Bibliográficos
Autores principales: de Araújo Pimenta, Luciana, de Almeida, Maíra Estanislau S., Bretones, Marisa Langeani, Cirillo, Maria Cristina, Curi, Rui, Sampaio, Sandra Coccuzzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414609/
https://www.ncbi.nlm.nih.gov/pubmed/30862840
http://dx.doi.org/10.1038/s41598-019-40903-0