Cargando…
Crotoxin promotes macrophage reprogramming towards an antiangiogenic phenotype
Crotoxin (CTX) is the primary toxin of South American rattlesnake Crotalus durissus terrificus venom. CTX reduces tumour mass, and tumour cell proliferation and these effects seem to involve the formation of new vessels. Angiogenesis has a key role in tumour growth and progression and is regulated b...
Autores principales: | de Araújo Pimenta, Luciana, de Almeida, Maíra Estanislau S., Bretones, Marisa Langeani, Cirillo, Maria Cristina, Curi, Rui, Sampaio, Sandra Coccuzzo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414609/ https://www.ncbi.nlm.nih.gov/pubmed/30862840 http://dx.doi.org/10.1038/s41598-019-40903-0 |
Ejemplares similares
-
Crotoxin Modulates Macrophage Phenotypic Reprogramming
por: Neves, Camila Lima, et al.
Publicado: (2023) -
Crotoxin Inhibits Endothelial Cell Functions in Two- and Three-dimensional Tumor Microenvironment
por: Kato, Ellen Emi, et al.
Publicado: (2021) -
Crotoxin Modulates Events Involved in Epithelial–Mesenchymal Transition in 3D Spheroid Model
por: Kato, Ellen Emi, et al.
Publicado: (2021) -
Walker 256 Tumor Growth Suppression by Crotoxin Involves Formyl Peptide Receptors and Lipoxin A(4)
por: Brigatte, Patrícia, et al.
Publicado: (2016) -
Immunotherapeutic potential of Crotoxin: anti-inflammatory and immunosuppressive properties
por: Sartim, Marco Aurélio, et al.
Publicado: (2018)