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Integrated analysis of relapsed B-cell precursor Acute Lymphoblastic Leukemia identifies subtype-specific cytokine and metabolic signatures

Recent efforts reclassified B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) into more refined subtypes. Nevertheless, outcomes of relapsed BCP-ALL remain unsatisfactory, particularly in adult patients where the molecular basis of relapse is still poorly understood. To elucidate the evolution...

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Detalles Bibliográficos
Autores principales: Schroeder, Michael P., Bastian, Lorenz, Eckert, Cornelia, Gökbuget, Nicola, James, Alva Rani, Tanchez, Jutta Ortiz, Schlee, Cornelia, Isaakidis, Konstandina, Häupl, Björn, Baum, Katharina, Migueles Lozano, Oscar Arturo, Kouidri, Khouloud, Pan, Kuan-Ting, Urlaub, Henning, Schwartz, Stefan, Burmeister, Thomas, von Stackelberg, Arend, Hoelzer, Dieter, Pfeiffer, Heike, Rieger, Michael A., Göllner, Stefanie, Oellerich, Thomas, Horstman, Martin, Schrappe, Martin, Wolf, Jana, Kirschner-Schwabe, Renate, Brüggemann, Monika, Müller-Tidow, Carsten, Serve, Hubert, Neumann, Martin, Baldus, Claudia D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414622/
https://www.ncbi.nlm.nih.gov/pubmed/30862934
http://dx.doi.org/10.1038/s41598-019-40786-1