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Deletion of tumour necrosis factor α receptor 1 elicits an increased TH17 immune response in the chronically inflamed liver

Tumour necrosis factor α receptor 1 (TNFR1) activation is known to induce cell death, inflammation, and fibrosis but also hepatocyte survival and regeneration. The multidrug resistance protein 2 knockout (Mdr2(−/)) mice are a model for chronic hepatitis and inflammation-associated hepatocellular car...

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Detalles Bibliográficos
Autores principales: Berkhout, Laura, Barikbin, Roja, Schiller, Birgit, Ravichandran, Gevitha, Krech, Till, Neumann, Katrin, Sass, Gabriele, Tiegs, Gisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414655/
https://www.ncbi.nlm.nih.gov/pubmed/30862875
http://dx.doi.org/10.1038/s41598-019-40324-z