Increased risk for T cell autoreactivity to ß-cell antigens in the mice expressing the A(vy) obesity-associated gene

There has been considerable debate as to whether obesity can act as an accelerator of type 1 diabetes (T1D). We assessed this possibility using transgenic mice (MIP-TF mice) whose ß-cells express enhanced green fluorescent protein (EGFP). Infecting these mice with EGFP-expressing murine herpes virus...

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Detalles Bibliográficos
Autores principales: Yong, Jing, Tian, Jide, Dang, Hoa, Wu, Ting-Ting, Atkinson, Mark A., Sun, Ren, Kaufman, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414670/
https://www.ncbi.nlm.nih.gov/pubmed/30862859
http://dx.doi.org/10.1038/s41598-019-38905-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414670/
https://www.ncbi.nlm.nih.gov/pubmed/30862859
http://dx.doi.org/10.1038/s41598-019-38905-z

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