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Broad and Protective Influenza B Virus Neuraminidase Antibodies in Humans after Vaccination and their Clonal Persistence as Plasma Cells

Although most seasonal inactivated influenza vaccines (IIV) contain neuraminidase (NA), the extent and mechanisms of action of protective human NA-specific humoral responses induced by vaccination are poorly resolved. Due to the propensity of influenza virus for antigenic drift and shift and its ten...

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Detalles Bibliográficos
Autores principales: Piepenbrink, Michael S., Nogales, Aitor, Basu, Madhubanti, Fucile, Christopher F., Liesveld, Jane L., Keefer, Michael C., Rosenberg, Alexander F., Martinez-Sobrido, Luis, Kobie, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414695/
https://www.ncbi.nlm.nih.gov/pubmed/30862743
http://dx.doi.org/10.1128/mBio.00066-19