Targeting Multidrug-Resistant Acinetobacter spp.: Sulbactam and the Diazabicyclooctenone β-Lactamase Inhibitor ETX2514 as a Novel Therapeutic Agent

Multidrug-resistant (MDR) Acinetobacter spp. poses a significant therapeutic challenge in part due to the presence of chromosomally encoded β-lactamases, including class C Acinetobacter-derived cephalosporinases (ADC) and class D oxacillinases (OXA), as well as plasmid-mediated class A β-lactamases....

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Detalles Bibliográficos
Autores principales: Barnes, Melissa D., Kumar, Vijay, Bethel, Christopher R., Moussa, Samir H., O’Donnell, John, Rutter, Joseph D., Good, Caryn E., Hujer, Kristine M., Hujer, Andrea M., Marshall, Steve H., Kreiswirth, Barry N., Richter, Sandra S., Rather, Philip N., Jacobs, Michael R., Papp-Wallace, Krisztina M., van den Akker, Focco, Bonomo, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414696/
https://www.ncbi.nlm.nih.gov/pubmed/30862744
http://dx.doi.org/10.1128/mBio.00159-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414696/
https://www.ncbi.nlm.nih.gov/pubmed/30862744
http://dx.doi.org/10.1128/mBio.00159-19

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