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Cerebrospinal Fluid Spermidine, Glutamine and Putrescine Predict Postoperative Delirium Following Elective Orthopaedic Surgery

Delirium is a marker of brain vulnerability, associated with increasing age, pre-existing cognitive impairment and, recently, cerebrospinal fluid (CSF) biomarkers of Alzheimer’s disease. This nested case-control study used a targeted quantitative metabolomic methodology to profile the preoperative C...

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Detalles Bibliográficos
Autores principales: Pan, Xiaobei, Cunningham, Emma L., Passmore, Anthony P., McGuinness, Bernadette, McAuley, Daniel F., Beverland, David, O’Brien, Seamus, Mawhinney, Tim, Schott, Jonathan M., Zetterberg, Henrik, Green, Brian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414730/
https://www.ncbi.nlm.nih.gov/pubmed/30862889
http://dx.doi.org/10.1038/s41598-019-40544-3