Cargando…

Cerebrospinal Fluid Spermidine, Glutamine and Putrescine Predict Postoperative Delirium Following Elective Orthopaedic Surgery

Delirium is a marker of brain vulnerability, associated with increasing age, pre-existing cognitive impairment and, recently, cerebrospinal fluid (CSF) biomarkers of Alzheimer’s disease. This nested case-control study used a targeted quantitative metabolomic methodology to profile the preoperative C...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pan, Xiaobei, Cunningham, Emma L., Passmore, Anthony P., McGuinness, Bernadette, McAuley, Daniel F., Beverland, David, O’Brien, Seamus, Mawhinney, Tim, Schott, Jonathan M., Zetterberg, Henrik, Green, Brian D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414730/ https://www.ncbi.nlm.nih.gov/pubmed/30862889 http://dx.doi.org/10.1038/s41598-019-40544-3

Ejemplares similares

Factors influencing resilience to postoperative delirium in adults undergoing elective orthopaedic surgery
por: Bowman, Emily M L, et al.
Publicado: (2022)

The Influence of Orthopedic Surgery on Circulating Metabolite Levels, and their Associations with the Incidence of Postoperative Delirium
por: Jung, Mijin, et al.
Publicado: (2022)

Evolution of the key alkaloid enzyme putrescine N-methyltransferase from spermidine synthase
por: Junker, Anne, et al.
Publicado: (2013)

Fine-tuning spermidine binding modes in the putrescine binding protein PotF
por: Kröger, Pascal, et al.
Publicado: (2021)

Pattern preferences of DNA nucleotide motifs by polyamines putrescine(2+), spermidine(3+) and spermine(4+)
por: Perepelytsya, Sergiy, et al.
Publicado: (2019)

Metabolomics and computational analysis of the role of monoamine oxidase activity in delirium and SARS-COV-2 infection
por: Cuperlovic-Culf, Miroslava, et al.
Publicado: (2021)

‘Excited Delirium’, acute behavioural disturbance, death and diagnosis
por: McGuinness, Terry, et al.
Publicado: (2022)

Pentafluoropropionic Anhydride Derivatization and GC-MS Analysis of Histamine, Agmatine, Putrescine, and Spermidine: Effects of Solvents and Starting Column Temperature
por: Tsikas, Dimitrios, et al.
Publicado: (2023)

Living alone for people on dementia medication: related use of drugs
por: Zafeiridi, Evi, et al.
Publicado: (2020)

Factors influencing transition to care homes for people with dementia in Northern Ireland
por: Zafeiridi, Evi, et al.
Publicado: (2021)

Evidence That Parietal Lobe Fatty Acids May Be More Profoundly Affected in Moderate Alzheimer’s Disease (AD) Pathology Than in Severe AD Pathology
por: Nasaruddin, Muhammad L., et al.
Publicado: (2018)

Metabolomic Profiling of Bile Acids in Clinical and Experimental Samples of Alzheimer’s Disease
por: Pan, Xiaobei, et al.
Publicado: (2017)

Role of exogenous putrescine in the status of energy, DNA damage, inflammation, and spermidine/spermine-n(1)- acetyltransferase in brain ischemia-reperfusion in rats
por: Cetin, Nihal, et al.
Publicado: (2022)

Factors Associated with Mortality Including Nursing Home Transitions: A Retrospective Analysis of 25,418 People Prescribed Anti-Dementia Drugs in Northern Ireland
por: McMichael, Alan J., et al.
Publicado: (2020)

Author response to: Factors influencing resilience to postoperative delirium in adults undergoing elective orthopaedic surgery
por: Cunningham, Emma L, et al.
Publicado: (2022)

Delirium in COVID-19: can we make the unknowns knowns?
por: Wilcox, M. Elizabeth, et al.
Publicado: (2021)

Predicting conversion to dementia in a memory clinic: A standard clinical approach compared with an empirically defined clustering method (latent profile analysis) for mild cognitive impairment subtyping
por: McGuinness, Bernadette, et al.
Publicado: (2015)

Platelet Membrane β-Secretase Activity in Mild Cognitive Impairment and Conversion to Dementia: a Longitudinal Study
por: McGuinness, Bernadette, et al.
Publicado: (2015)

Routine delirium monitoring in a UK critical care unit
por: Page, Valerie J, et al.
Publicado: (2009)

Alternative pathways utilize or circumvent putrescine for biosynthesis of putrescine-containing rhizoferrin
por: Li, Bin, et al.
Publicado: (2020)

Dementia
por: Cunningham, EL, et al.
Publicado: (2015)

Plasma neurofilament light chain protein as a predictor of days in delirium and deep sedation, mortality and length of stay in critically ill patients
por: Page, Valerie J, et al.
Publicado: (2022)

Phenotypes and subphenotypes of delirium: a review of current categorisations and suggestions for progression
por: Bowman, Emily M. L., et al.
Publicado: (2021)

Improving the Standard of Orthopaedic Operation Documentation Using Typed Proforma Operation Notes: A Completed Audit Loop
por: Coughlan, Fionn, et al.
Publicado: (2017)

Diet and Inflammation in Cognitive Ageing and Alzheimer’s Disease
por: McGrattan, Andrea M., et al.
Publicado: (2019)

How useful is dual energy lateral vertebral assessment in a clinic setting?
por: McGuinness, Bernadette, et al.
Publicado: (2009)

Impact of non-pharmacological interventions on prevention and treatment of delirium in critically ill patients: protocol for a systematic review of quantitative and qualitative research
por: Bannon, Leona, et al.
Publicado: (2016)

Evaluating early administration of the hydroxymethylglutaryl-CoA reductase inhibitor simvastatin in the prevention and treatment of delirium in critically ill ventilated patients (MoDUS trial): study protocol for a randomized controlled trial
por: Casarin, Annalisa, et al.
Publicado: (2015)

Putrescine accumulation in human pulmonary tumours.
por: Hoet, P. H., et al.
Publicado: (1996)

Production of Putrescine and Cadaverine by Paucilactobacillus wasatchensis
por: Berthoud, Hélène, et al.
Publicado: (2022)

Putrescine Detected in Strains of Staphylococcus aureus
por: Seravalli, Javier, et al.
Publicado: (2023)

Plasma glutamine after acute or elective admission on the ICU
por: Buter, H, et al.
Publicado: (2015)

Durability of Smoking Cessation for Elective Lower Extremity Orthopaedic Surgery
por: Smith, Danica H., et al.
Publicado: (2019)

Serum concentrations of vitamin E and carotenoids are altered in Alzheimer's disease: A case-control study
por: Mullan, Kathryn, et al.
Publicado: (2017)

Serum xanthophyll carotenoids are associated with estimated glomerular filtration rate in an aged cohort
por: Browne, Declan, et al.
Publicado: (2019)

Plasma glutamine levels in patients after non-elective or elective ICU admission: an observational study
por: Buter, Hanneke, et al.
Publicado: (2016)

Peri-ovulatory putrescine to reduce aneuploid conceptions
por: Liu, X. Johné, et al.
Publicado: (2012)

Effects of putrescine on the postharvest physiology characteristics in cowpea
por: Wang, Zhen, et al.
Publicado: (2019)

Advanced pathway engineering for phototrophic putrescine production
por: Freudenberg, Robert A., et al.
Publicado: (2022)

Transcriptome Profile of Fusarium graminearum Treated by Putrescine
por: Zhang, Lina, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_e611t5fa8r905br43cjctm7ujf