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Site-Specific DBCO Modification of DEC205 Antibody for Polymer Conjugation

The design of multifunctional polymer-based vectors, forming pDNA vaccines, offers great potential in cancer immune therapy. The transfection of dendritic immune cells (DCs) with tumour antigen-encoding pDNA leads to an activation of the immune system to combat tumour cells. In this work, we investi...

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Detalles Bibliográficos
Autores principales: Beck, Simone, Schultze, Jennifer, Räder, Hans-Joachim, Holm, Regina, Schinnerer, Meike, Barz, Matthias, Koynov, Kaloian, Zentel, Rudolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414842/
https://www.ncbi.nlm.nih.gov/pubmed/30966177
http://dx.doi.org/10.3390/polym10020141