Rheo-Kinetic Study of Sol-Gel Phase Transition of Chitosan Colloidal Systems

Chitosan colloidal systems, created by dispersing in aqueous solutions of hydrochloric acid, with and without the addition of disodium β-glycerophosphate (β-NaGP), were prepared for the investigation of forming mechanisms of chitosan hydrogels. Three types of chitosan were used in varying molecular...

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Autores principales: Owczarz, Piotr, Ziółkowski, Patryk, Modrzejewska, Zofia, Kuberski, Sławomir, Dziubiński, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414863/
https://www.ncbi.nlm.nih.gov/pubmed/30966083
http://dx.doi.org/10.3390/polym10010047
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author Owczarz, Piotr
Ziółkowski, Patryk
Modrzejewska, Zofia
Kuberski, Sławomir
Dziubiński, Marek
author_facet Owczarz, Piotr
Ziółkowski, Patryk
Modrzejewska, Zofia
Kuberski, Sławomir
Dziubiński, Marek
author_sort Owczarz, Piotr
collection PubMed
description Chitosan colloidal systems, created by dispersing in aqueous solutions of hydrochloric acid, with and without the addition of disodium β-glycerophosphate (β-NaGP), were prepared for the investigation of forming mechanisms of chitosan hydrogels. Three types of chitosan were used in varying molecular weights. The impacts of the charge and shape of the macromolecules on the phase transition process were assessed. The chitosan system without the addition of β-NaGP was characterized by stiff and entangled molecules, in contrast to the chitosan system with the addition of β-NaGP, wherein the molecules adopt a more flexible and disentangled form. Differences in molecules shapes were confirmed using the Zeta potential and thixotropy experiments. The chitosan system without β-NaGP revealed a rapid nature of phase transition—consistent with diffusion-limited aggregation (DLA). The chitosan system with β-NaGP revealed a two-step nature of phase transition, wherein the first step was consistent with reaction-limited aggregation (RLA), while the second step complied with diffusion-limited aggregation (DLA).
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spelling pubmed-64148632019-04-02 Rheo-Kinetic Study of Sol-Gel Phase Transition of Chitosan Colloidal Systems Owczarz, Piotr Ziółkowski, Patryk Modrzejewska, Zofia Kuberski, Sławomir Dziubiński, Marek Polymers (Basel) Article Chitosan colloidal systems, created by dispersing in aqueous solutions of hydrochloric acid, with and without the addition of disodium β-glycerophosphate (β-NaGP), were prepared for the investigation of forming mechanisms of chitosan hydrogels. Three types of chitosan were used in varying molecular weights. The impacts of the charge and shape of the macromolecules on the phase transition process were assessed. The chitosan system without the addition of β-NaGP was characterized by stiff and entangled molecules, in contrast to the chitosan system with the addition of β-NaGP, wherein the molecules adopt a more flexible and disentangled form. Differences in molecules shapes were confirmed using the Zeta potential and thixotropy experiments. The chitosan system without β-NaGP revealed a rapid nature of phase transition—consistent with diffusion-limited aggregation (DLA). The chitosan system with β-NaGP revealed a two-step nature of phase transition, wherein the first step was consistent with reaction-limited aggregation (RLA), while the second step complied with diffusion-limited aggregation (DLA). MDPI 2018-01-05 /pmc/articles/PMC6414863/ /pubmed/30966083 http://dx.doi.org/10.3390/polym10010047 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Owczarz, Piotr
Ziółkowski, Patryk
Modrzejewska, Zofia
Kuberski, Sławomir
Dziubiński, Marek
Rheo-Kinetic Study of Sol-Gel Phase Transition of Chitosan Colloidal Systems
title Rheo-Kinetic Study of Sol-Gel Phase Transition of Chitosan Colloidal Systems
title_full Rheo-Kinetic Study of Sol-Gel Phase Transition of Chitosan Colloidal Systems
title_fullStr Rheo-Kinetic Study of Sol-Gel Phase Transition of Chitosan Colloidal Systems
title_full_unstemmed Rheo-Kinetic Study of Sol-Gel Phase Transition of Chitosan Colloidal Systems
title_short Rheo-Kinetic Study of Sol-Gel Phase Transition of Chitosan Colloidal Systems
title_sort rheo-kinetic study of sol-gel phase transition of chitosan colloidal systems
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414863/
https://www.ncbi.nlm.nih.gov/pubmed/30966083
http://dx.doi.org/10.3390/polym10010047
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