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Hydrogen-Deuterium Exchange Profiles of Polyubiquitin Fibrils

Ubiquitin and its polymeric forms are conjugated to intracellular proteins to regulate diverse intracellular processes. Intriguingly, polyubiquitin has also been identified as a component of pathological protein aggregates associated with Alzheimer’s disease and other neurodegenerative disorders. We...

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Detalles Bibliográficos
Autores principales: Morimoto, Daichi, Nishizawa, Ryo, Walinda, Erik, Takashima, Shingo, Sugase, Kenji, Shirakawa, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414897/
https://www.ncbi.nlm.nih.gov/pubmed/30966275
http://dx.doi.org/10.3390/polym10030240