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Hydrogen-Deuterium Exchange Profiles of Polyubiquitin Fibrils
Ubiquitin and its polymeric forms are conjugated to intracellular proteins to regulate diverse intracellular processes. Intriguingly, polyubiquitin has also been identified as a component of pathological protein aggregates associated with Alzheimer’s disease and other neurodegenerative disorders. We...
Autores principales: | Morimoto, Daichi, Nishizawa, Ryo, Walinda, Erik, Takashima, Shingo, Sugase, Kenji, Shirakawa, Masahiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414897/ https://www.ncbi.nlm.nih.gov/pubmed/30966275 http://dx.doi.org/10.3390/polym10030240 |
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