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Hypoxia-Responsive Mesoporous Nanoparticles for Doxorubicin Delivery

Hypoxia, or low oxygen tension, is a common feature of solid tumors. Here, we report hypoxia-responsive mesoporous silica nanoparticles (HR-MSNs) with a 4-nitroimidazole-β-cyclodextrin (NI-CD) complex that is acting as the hypoxia-responsive gatekeeper. When these CD-HR-MSNs encountered a hypoxic en...

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Detalles Bibliográficos
Autores principales: Khatoon, Shakera, Han, Hwa Seung, Jeon, Jueun, Rao, N. Vijayakameswara, Jeong, Dae-Woong, Ikram, M., Yasin, T., Yi, Gi-Ra, Park, Jae Hyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415200/
https://www.ncbi.nlm.nih.gov/pubmed/30966424
http://dx.doi.org/10.3390/polym10040390