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Comparative Study of Diethylaminoethyl-Chitosan and Methylglycol-Chitosan as Potential Non-Viral Vectors for Gene Therapy

In this paper, we compared the transfection efficiency and cytotoxicity of methylglycol-chitosan (MG-CS) and diethylaminoethyl-chitosan (DEAE-CS(I) and DEAE-CS(II) with degrees of substitution of 1.2 and 0.57, respectively) to that of Lipofectamine (used as a reference transfection vector). MG-CS co...

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Detalles Bibliográficos
Autores principales: Raik, Sergei V., Andranovitš, Stanislav, Petrova, Valentina A., Xu, Yingying, Lam, Jenny Ka-Wing, Morris, Gordon A., Brodskaia, Alexandra V., Casettari, Luca, Kritchenkov, Andreii S., Skorik, Yury A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415247/
https://www.ncbi.nlm.nih.gov/pubmed/30966477
http://dx.doi.org/10.3390/polym10040442