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The Length of Hydrophobic Chain in Amphiphilic Polypeptides Regulates the Efficiency of Gene Delivery

The major challenges of non-viral carriers are low transfection efficiency and high toxicity. To overcome this bottleneck, it is very important to investigate the structure-property-function (transfection efficiency) relationships of polycations. Herein, different length hydrophobic poly(l-leucine)...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Zhou, Zhiping, Chen, Mingsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415248/
https://www.ncbi.nlm.nih.gov/pubmed/30966414
http://dx.doi.org/10.3390/polym10040379