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Molecular Weight-Dependent Activity of Aminated Poly(α)glutamates as siRNA Nanocarriers

RNA interference (RNAi) can contribute immensely to the area of personalized medicine by its ability to target any gene of interest. Nevertheless, its clinical use is limited by lack of efficient delivery systems. Polymer therapeutics can address many of the challenges encountered by the systemic de...

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Detalles Bibliográficos
Autores principales: Krivitsky, Adva, Krivitsky, Vadim, Polyak, Dina, Scomparin, Anna, Eliyahu, Shay, Gibori, Hadas, Yeini, Eilam, Pisarevsky, Evgeni, Blau, Rachel, Satchi-Fainaro, Ronit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415365/
https://www.ncbi.nlm.nih.gov/pubmed/30966582
http://dx.doi.org/10.3390/polym10050548