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Exercise endurance capacity is markedly reduced due to impaired energy homeostasis during prolonged fasting in FABP4/5 deficient mice

BACKGROUND: Skeletal muscle prefers carbohydrate use to fatty acid (FA) use as exercise intensity increases. In contrast, skeletal muscle minimizes glucose use and relies more on FA during fasting. In mice deficient for FABP4 and FABP5 (double knockout (DKO) mice), FA utilization by red skeletal mus...

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Detalles Bibliográficos
Autores principales: Iso, Tatsuya, Haruyama, Hikari, Sunaga, Hiroaki, Matsui, Miki, Matsui, Hiroki, Tanaka, Rina, Umbarawan, Yogi, Syamsunarno, Mas Rizky A. A., Yokoyama, Tomoyuki, Kurabayashi, Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415495/
https://www.ncbi.nlm.nih.gov/pubmed/30866899
http://dx.doi.org/10.1186/s12899-019-0038-6