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Caffeine Treatment Promotes Differentiation and Maturation of Hypoxic Oligodendrocytes via Counterbalancing Adenosine 1 Adenosine Receptor-Induced Calcium Overload

BACKGROUND: We aimed to explore the involvement of adenosine 1 adenosine receptor (A1AR) in hypoxia-induced poor differentiation of oligodendrocytes (OLs), and the underlying mechanism of caffeine treatment in hypoxic injuries. MATERIAL/METHODS: Real-time polymerase chain reaction (RT-PCR) was used...

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Detalles Bibliográficos
Autores principales: Cao, Ting, Ma, Teng, Xu, Yang, Tian, Yanping, Cai, Qiyan, Li, Baichuan, Li, Hongli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415592/
https://www.ncbi.nlm.nih.gov/pubmed/30840612
http://dx.doi.org/10.12659/MSM.915147