Additional value of a combined genetic risk score to standard cardiovascular stratification

The utility of genetic risk scores (GRS) as independent risk predictors remains inconclusive. Here, we evaluate the additive value of a multi-locus GRS to the Framingham risk score (FRS) in coronary artery disease (CAD) risk prediction. A total of 2888 individuals (1566 coronary patients and 1322 co...

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Detalles Bibliográficos
Autores principales: Pereira, Andreia, Mendonca, Maria Isabel, Borges, Sofia, Sousa, Ana Célia, Freitas, Sónia, Henriques, Eva, Rodrigues, Mariana, Freitas, Ana Isabel, Guerra, Graça, Freitas, Carolina, Pereira, Décio, Brehm, António, Reis, Roberto Palma Dos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2018
Materias:
Human and Medical Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415604/
https://www.ncbi.nlm.nih.gov/pubmed/30571812
http://dx.doi.org/10.1590/1678-4685-GMB-2017-0173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415604/
https://www.ncbi.nlm.nih.gov/pubmed/30571812
http://dx.doi.org/10.1590/1678-4685-GMB-2017-0173

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