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Additional value of a combined genetic risk score to standard cardiovascular stratification

The utility of genetic risk scores (GRS) as independent risk predictors remains inconclusive. Here, we evaluate the additive value of a multi-locus GRS to the Framingham risk score (FRS) in coronary artery disease (CAD) risk prediction. A total of 2888 individuals (1566 coronary patients and 1322 co...

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Detalles Bibliográficos
Autores principales:	Pereira, Andreia, Mendonca, Maria Isabel, Borges, Sofia, Sousa, Ana Célia, Freitas, Sónia, Henriques, Eva, Rodrigues, Mariana, Freitas, Ana Isabel, Guerra, Graça, Freitas, Carolina, Pereira, Décio, Brehm, António, Reis, Roberto Palma Dos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Sociedade Brasileira de Genética 2018
Materias:	Human and Medical Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415604/ https://www.ncbi.nlm.nih.gov/pubmed/30571812 http://dx.doi.org/10.1590/1678-4685-GMB-2017-0173

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