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Chronic myelogenous leukemia, a still unsolved problem: pitfalls and new therapeutic possibilities

Chronic myeloid leukemia (CML) is a clonal myeloproliferative disorder of hematopoietic stem cells. At the molecular level, the disorder results from t(9;22)(q34;q11) reciprocal translocation between chromosomes, which leads to the formation of an oncogenic BCR–ABL gene fusion. Instead of progress i...

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Detalles Bibliográficos
Autores principales: Flis, Sylwia, Chojnacki, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415732/
https://www.ncbi.nlm.nih.gov/pubmed/30880916
http://dx.doi.org/10.2147/DDDT.S191303