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Chronic myelogenous leukemia, a still unsolved problem: pitfalls and new therapeutic possibilities
Chronic myeloid leukemia (CML) is a clonal myeloproliferative disorder of hematopoietic stem cells. At the molecular level, the disorder results from t(9;22)(q34;q11) reciprocal translocation between chromosomes, which leads to the formation of an oncogenic BCR–ABL gene fusion. Instead of progress i...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415732/ https://www.ncbi.nlm.nih.gov/pubmed/30880916 http://dx.doi.org/10.2147/DDDT.S191303 |