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Unbiased pattern analysis reveals highly diverse responses of cytoskeletal systems to cyclic straining

In mammalian cells, actin, microtubules, and various types of cytoplasmic intermediate filaments respond to external stretching. Here, we investigated the underlying processes in endothelial cells plated on soft substrates from silicone elastomer. After cyclic stretch (0.13 Hz, 14% strain amplitude)...

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Detalles Bibliográficos
Autores principales: Springer, Ronald, Zielinski, Alexander, Pleschka, Catharina, Hoffmann, Bernd, Merkel, Rudolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415792/
https://www.ncbi.nlm.nih.gov/pubmed/30865622
http://dx.doi.org/10.1371/journal.pone.0210570