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Ketamine disrupts neuromodulatory control of glutamatergic synaptic transmission

A growing body of literature has demonstrated the potential for ketamine in the treatment of major depression. Sub-anesthetic doses produce rapid and sustained changes in depressive behavior, both in patients and rodent models, associated with reorganization of glutamatergic synapses in the prefront...

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Detalles Bibliográficos
Autores principales: Lur, Gyorgy, Fariborzi, Mona, Higley, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415832/
https://www.ncbi.nlm.nih.gov/pubmed/30865708
http://dx.doi.org/10.1371/journal.pone.0213721