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The C-terminal region of Net1 is an activator of RNA polymerase I transcription with conserved features from yeast to human
RNA polymerase I (Pol I) synthesizes ribosomal RNA (rRNA) in all eukaryotes, accounting for the major part of transcriptional activity in proliferating cells. Although basal Pol I transcription factors have been characterized in diverse organisms, the molecular basis of the robust rRNA production in...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415870/ https://www.ncbi.nlm.nih.gov/pubmed/30802237 http://dx.doi.org/10.1371/journal.pgen.1008006 |