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NAP (davunetide) preferential interaction with dynamic 3-repeat Tau explains differential protection in selected tauopathies
The microtubule (MT) associated protein Tau is instrumental for the regulation of MT assembly and dynamic instability, orchestrating MT-dependent cellular processes. Aberration in Tau post-translational modifications ratio deviation of spliced Tau isoforms 3 or 4 MT binding repeats (3R/4R) have been...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415897/ https://www.ncbi.nlm.nih.gov/pubmed/30865715 http://dx.doi.org/10.1371/journal.pone.0213666 |