Connexin-43-dependent ATP release mediates macrophage activation during sepsis

Bacterial spillage into a sterile environment following intestinal hollow-organ perforation leads to peritonitis and fulminant sepsis. Outcome of sepsis critically depends on macrophage activation by extracellular ATP-release and associated autocrine signalling via purinergic receptors. ATP-release...

Descripción completa

Detalles Bibliográficos
Autores principales: Dosch, Michel, Zindel, Joël, Jebbawi, Fadi, Melin, Nicolas, Sanchez-Taltavull, Daniel, Stroka, Deborah, Candinas, Daniel, Beldi, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415938/
https://www.ncbi.nlm.nih.gov/pubmed/30735126
http://dx.doi.org/10.7554/eLife.42670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415938/
https://www.ncbi.nlm.nih.gov/pubmed/30735126
http://dx.doi.org/10.7554/eLife.42670

Ejemplares similares