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Connexin-43-dependent ATP release mediates macrophage activation during sepsis
Bacterial spillage into a sterile environment following intestinal hollow-organ perforation leads to peritonitis and fulminant sepsis. Outcome of sepsis critically depends on macrophage activation by extracellular ATP-release and associated autocrine signalling via purinergic receptors. ATP-release...
Autores principales: | Dosch, Michel, Zindel, Joël, Jebbawi, Fadi, Melin, Nicolas, Sanchez-Taltavull, Daniel, Stroka, Deborah, Candinas, Daniel, Beldi, Guido |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415938/ https://www.ncbi.nlm.nih.gov/pubmed/30735126 http://dx.doi.org/10.7554/eLife.42670 |
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