The proteasome biogenesis regulator Rpn4 cooperates with the unfolded protein response to promote ER stress resistance

Misfolded proteins in the endoplasmic reticulum (ER) activate the unfolded protein response (UPR), which enhances protein folding to restore homeostasis. Additional pathways respond to ER stress, but how they help counteract protein misfolding is incompletely understood. Here, we develop a titratabl...

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Detalles Bibliográficos
Autores principales: Schmidt, Rolf M, Schessner, Julia P, Borner, Georg HH, Schuck, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415940/
https://www.ncbi.nlm.nih.gov/pubmed/30865586
http://dx.doi.org/10.7554/eLife.43244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415940/
https://www.ncbi.nlm.nih.gov/pubmed/30865586
http://dx.doi.org/10.7554/eLife.43244

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