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Human pluripotent stem cell–derived brain pericyte–like cells induce blood-brain barrier properties

Brain pericytes play important roles in the formation and maintenance of the neurovascular unit (NVU), and their dysfunction has been implicated in central nervous system disorders. While human pluripotent stem cells (hPSCs) have been used to model other NVU cell types, including brain microvascular...

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Detalles Bibliográficos
Autores principales: Stebbins, Matthew J., Gastfriend, Benjamin D., Canfield, Scott G., Lee, Ming-Song, Richards, Drew, Faubion, Madeline G., Li, Wan-Ju, Daneman, Richard, Palecek, Sean P., Shusta, Eric V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415958/
https://www.ncbi.nlm.nih.gov/pubmed/30891496
http://dx.doi.org/10.1126/sciadv.aau7375