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Rapid and inefficient kinetics of sickle hemoglobin fiber growth

In sickle cell disease, the aberrant assembly of hemoglobin fibers induces changes in red blood cell morphology and stiffness, which leads to downstream symptoms of the disease. Therefore, understanding of this assembly process will be important for the treatment of sickle cell disease. By performin...

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Detalles Bibliográficos
Autores principales: Castle, Brian T., Odde, David J., Wood, David K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415962/
https://www.ncbi.nlm.nih.gov/pubmed/30891490
http://dx.doi.org/10.1126/sciadv.aau1086