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Rapid and inefficient kinetics of sickle hemoglobin fiber growth
In sickle cell disease, the aberrant assembly of hemoglobin fibers induces changes in red blood cell morphology and stiffness, which leads to downstream symptoms of the disease. Therefore, understanding of this assembly process will be important for the treatment of sickle cell disease. By performin...
Autores principales: | Castle, Brian T., Odde, David J., Wood, David K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415962/ https://www.ncbi.nlm.nih.gov/pubmed/30891490 http://dx.doi.org/10.1126/sciadv.aau1086 |
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