Cargando…

Influenza virus polymerase inhibitors in clinical development

PURPOSE OF REVIEW: We review antivirals inhibiting subunits of the influenza polymerase complex that are advancing in clinical development. RECENT FINDINGS: Favipiravir, pimodivir, and baloxavir are inhibitory in preclinical models for influenza A viruses, including pandemic threat viruses and those...

Descripción completa

Detalles Bibliográficos
Autores principales: Hayden, Frederick G., Shindo, Nahoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416007/
https://www.ncbi.nlm.nih.gov/pubmed/30724789
http://dx.doi.org/10.1097/QCO.0000000000000532