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Interleukin-18 exacerbates skin inflammation and affects microabscesses and scale formation in a mouse model of imiquimod-induced psoriasis

BACKGROUND: As a potent pro-inflammatory cytokine of the interleukin (IL)-1 family, IL-18 was elevated in early active and progressive plaque-type psoriatic lesions and that serum or plasma levels of IL-18 correlated with the Psoriasis Area and Severity Index (PASI). Although results from previous s...

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Detalles Bibliográficos
Autores principales: Niu, Xue-Li, Huang, Yu, Gao, Ya-Li, Sun, Yu-Zhe, Han, Yang, Chen, Hong-Duo, Gao, Xing-Hua, Qi, Rui-Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416030/
https://www.ncbi.nlm.nih.gov/pubmed/30741833
http://dx.doi.org/10.1097/CM9.0000000000000140