CXCR6-Deficiency Improves the Control of Pulmonary Mycobacterium tuberculosis and Influenza Infection Independent of T-Lymphocyte Recruitment to the Lungs

T-lymphocytes are critical for protection against respiratory infections, such as Mycobacterium tuberculosis and influenza virus, with chemokine receptors playing an important role in directing these cells to the lungs. CXCR6 is expressed by activated T-lymphocytes and its ligand, CXCL16, is constit...

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Detalles Bibliográficos
Autores principales: Ashhurst, Anneliese S., Flórido, Manuela, Lin, Leon C. W., Quan, Diana, Armitage, Ellis, Stifter, Sebastian A., Stambas, John, Britton, Warwick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416161/
https://www.ncbi.nlm.nih.gov/pubmed/30899256
http://dx.doi.org/10.3389/fimmu.2019.00339