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Serum Amyloid A Stimulates Vascular and Renal Dysfunction in Apolipoprotein E-Deficient Mice Fed a Normal Chow Diet

Elevated serum amyloid A (SAA) levels may promote endothelial dysfunction, which is linked to cardiovascular and renal pathologies. We investigated the effect of SAA on vascular and renal function in apolipoprotein E-deficient (ApoE(−/−)) mice. Male ApoE(−/−) mice received vehicle (control), low-lev...

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Detalles Bibliográficos
Autores principales: Chami, Belal, Hossain, Farjaneh, Hambly, Thomas W., Cai, Xiaoping, Aran, Roshanak, Fong, Genevieve, Vellajo, Abigail, Martin, Nathan J.J, Wang, XiaoSuo, Dennis, Joanne M., Sharma, Arpeeta, Shihata, Waled A., Chin-Dusting, Jaye P. F., de Haan, Judy B., Sharland, Alexandra, Geczy, Carolyn L., Freedman, Ben, Witting, Paul K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416175/
https://www.ncbi.nlm.nih.gov/pubmed/30899260
http://dx.doi.org/10.3389/fimmu.2019.00380