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Tonic inhibition of murine proximal colon is due to nitrergic suppression of Ca(2+) signaling in interstitial cells of Cajal
Spontaneous excitability and contractions of colonic smooth muscle cells (SMCs) are normally suppressed by inputs from inhibitory motor neurons, a behavior known as tonic inhibition. The post-junctional cell(s) mediating tonic inhibition have not been elucidated. We investigated the post-junctional...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416298/ https://www.ncbi.nlm.nih.gov/pubmed/30867452 http://dx.doi.org/10.1038/s41598-019-39729-7 |