Identification of fibrinogen as a natural inhibitor of MMP-2

Non-genetic MMP-2 insufficiency is a relatively unexplored condition which could be induced by pathological overexpression of endogenous MMP-2 inhibitors such as TIMPs and/or the acute phase reactant alpha-2-macroglobulin. Here, we investigate the hypothesis that human fibrinogen (FBG) – an acute ph...

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Detalles Bibliográficos
Autores principales: Sarker, Hassan, Hardy, Eugenio, Haimour, Ayman, Maksymowych, Walter P., Botto, Lorenzo D., Fernandez-Patron, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416301/
https://www.ncbi.nlm.nih.gov/pubmed/30867536
http://dx.doi.org/10.1038/s41598-019-40983-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416301/
https://www.ncbi.nlm.nih.gov/pubmed/30867536
http://dx.doi.org/10.1038/s41598-019-40983-y

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