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DNA damage signalling from the placenta to foetal blood as a potential mechanism for childhood leukaemia initiation

For many diseases with a foetal origin, the cause for the disease initiation remains unknown. Common childhood acute leukaemia is thought to be caused by two hits, the first in utero and the second in childhood in response to infection. The mechanism for the initial DNA damaging event are unknown. H...

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Detalles Bibliográficos
Autores principales: Mansell, Els, Zareian, Nahid, Malouf, Camille, Kapeni, Chrysa, Brown, Natalie, Badie, Christophe, Baird, Duncan, Lane, Jon, Ottersbach, Katrin, Blair, Allison, Case, C. Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416312/
https://www.ncbi.nlm.nih.gov/pubmed/30867444
http://dx.doi.org/10.1038/s41598-019-39552-0