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PIP(3)-Phldb2 is crucial for LTP regulating synaptic NMDA and AMPA receptor density and PSD95 turnover

The essential involvement of phosphoinositides in synaptic plasticity is well-established, but incomplete knowledge of the downstream molecular entities prevents us from understanding their signalling cascades completely. Here, we determined that Phldb2, of which pleckstrin-homology domain is highly...

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Detalles Bibliográficos
Autores principales: Xie, Min-Jue, Ishikawa, Yasuyuki, Yagi, Hideshi, Iguchi, Tokuichi, Oka, Yuichiro, Kuroda, Kazuki, Iwata, Keiko, Kiyonari, Hiroshi, Matsuda, Shinji, Matsuzaki, Hideo, Yuzaki, Michisuke, Fukazawa, Yugo, Sato, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416313/
https://www.ncbi.nlm.nih.gov/pubmed/30867511
http://dx.doi.org/10.1038/s41598-019-40838-6