Cargando…
Low-dose pioglitazone can ameliorate learning and memory impairment in a mouse model of dementia by increasing LRP1 expression in the hippocampus
Amyloid-β (Aβ) accumulation in the brain is a pathological feature of Alzheimer’s disease (AD) and enhancing Aβ clearance is a potential therapeutic strategy. Pioglitazone is a peroxisome proliferator-activated receptor-γ (PPAR-γ) agonist and is widely used to treat type 2 diabetes. We previously re...
Autores principales: | Seok, Hannah, Lee, Minyoung, Shin, Eugene, Yun, Mi Ra, Lee, Yong-ho, Moon, Jae Hoon, Kim, Eosu, Lee, Phil Hyu, Lee, Byung-Wan, Kang, Eun Seok, Lee, Hyun Chul, Cha, Bong Soo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416325/ https://www.ncbi.nlm.nih.gov/pubmed/30867485 http://dx.doi.org/10.1038/s41598-019-40736-x |
Ejemplares similares
-
Ipragliflozin Additively Ameliorates Non-Alcoholic Fatty Liver Disease in Patients with Type 2 Diabetes Controlled with Metformin and Pioglitazone: A 24-Week Randomized Controlled Trial
por: Han, Eugene, et al.
Publicado: (2020) -
The Risk of Bladder Cancer in Korean Diabetic Subjects Treated with Pioglitazone
por: Song, Sun Ok, et al.
Publicado: (2012) -
Ipragliflozin, an SGLT2 Inhibitor, Ameliorates High-Fat Diet-Induced Metabolic Changes by Upregulating Energy Expenditure through Activation of the AMPK/ SIRT1 Pathway
por: Lee, Ji-Yeon, et al.
Publicado: (2021) -
Effect of Rivastigmine on Behavioral and Psychiatric Symptoms of Parkinson’s Disease Dementia
por: Oh, Yoon-Sang, et al.
Publicado: (2015) -
Neuropsychiatric Symptoms in Parkinson’s Disease Dementia Are Associated with Increased Caregiver Burden
por: Oh, Yoon-Sang, et al.
Publicado: (2015)