Contractile forces in platelet aggregates under microfluidic shear gradients reflect platelet inhibition and bleeding risk

Platelets contract forcefully after their activation, contributing to the strength and stability of platelet aggregates and fibrin clots during blood coagulation. Viscoelastic approaches can be used to assess platelet-induced clot strengthening, but they require thrombin and fibrin generation and ar...

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Detalles Bibliográficos
Autores principales: Ting, Lucas H., Feghhi, Shirin, Taparia, Nikita, Smith, Annie O., Karchin, Ari, Lim, Esther, John, Alex St., Wang, Xu, Rue, Tessa, White, Nathan J., Sniadecki, Nathan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416331/
https://www.ncbi.nlm.nih.gov/pubmed/30867419
http://dx.doi.org/10.1038/s41467-019-09150-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416331/
https://www.ncbi.nlm.nih.gov/pubmed/30867419
http://dx.doi.org/10.1038/s41467-019-09150-9

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