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Featherweight long read alignment using partitioned reference indexes

The advent of Nanopore sequencing has realised portable genomic research and applications. However, state of the art long read aligners and large reference genomes are not compatible with most mobile computing devices due to their high memory requirements. We show how memory requirements can be redu...

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Detalles Bibliográficos
Autores principales: Gamaarachchi, Hasindu, Parameswaran, Sri, Smith, Martin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416333/
https://www.ncbi.nlm.nih.gov/pubmed/30867495
http://dx.doi.org/10.1038/s41598-019-40739-8