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The LXR-623-induced long non-coding RNA LINC01125 suppresses the proliferation of breast cancer cells via PTEN/AKT/p53 signaling pathway

LXR-623 (WAY-252623), a liver X receptor agonist, reduces atherosclerotic plaque progression and remarkably inhibits the proliferation of glioblastoma cells, owing to its brain-penetrant ability. However, the role of LXR-623 against the proliferation of other cancer cells and the underlying mechanis...

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Detalles Bibliográficos
Autores principales: Wan, Weijun, Hou, Yongying, Wang, Ke, Cheng, Yue, Pu, Xia, Ye, Xiufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416354/
https://www.ncbi.nlm.nih.gov/pubmed/30867411
http://dx.doi.org/10.1038/s41419-019-1440-5