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Network-based prediction of drug combinations

Drug combinations, offering increased therapeutic efficacy and reduced toxicity, play an important role in treating multiple complex diseases. Yet, our ability to identify and validate effective combinations is limited by a combinatorial explosion, driven by both the large number of drug pairs as we...

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Detalles Bibliográficos
Autores principales: Cheng, Feixiong, Kovács, István A., Barabási, Albert-László
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416394/
https://www.ncbi.nlm.nih.gov/pubmed/30867426
http://dx.doi.org/10.1038/s41467-019-09186-x