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Thermodynamic and structural contributions of the 6-thioguanosine residue to helical properties of RNA

Thionucleotides, especially 4-thiouridine and 6-thioguanosine, are photosensitive molecules that photocrosslink to both proteins and nucleic acids, and this feature is a major reason for their application in various investigations. To get insight into the thermodynamic and structural contributions o...

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Detalles Bibliográficos
Autores principales: Gładysz, Michał, Andrałojć, Witold, Czapik, Tomasz, Gdaniec, Zofia, Kierzek, Ryszard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416399/
https://www.ncbi.nlm.nih.gov/pubmed/30867505
http://dx.doi.org/10.1038/s41598-019-40715-2